Products Description of SANDALORE CAS#65113‑99‑7
Sandalore is a synthetic sandal‑type fragrance ingredient delivering a scent highly comparable to natural sandalwood, which grants it broad application value in perfumes, emollients and skin‑cleansing formulations. Together with its analog brahmanol, Sandalore acts as an agonist for the skin olfactory receptor OR2AT4, and can trigger potent Ca²⁺ signaling responses in cultured human keratinocytes.
Prolonged treatment with Sandalore stimulates keratinocyte proliferation and cell migration, and accelerates monolayer regeneration in in‑vitro scratch‑wound tests. It delivers noticeable epidermal wound‑healing performance in human skin organ cultures — a unique biological property that cannot be observed with natural sandalwood oil or other synthetic sandalwood fragrances.
SANDALORE Chemical Properties
| Boiling point | 275.8±9.0 °C(Predicted) |
| Density | 0.895-0.904 |
| Refractive index | 1.4700-1.4760 |
| Fp | >100°C |
| Storage temp. | Refrigerator |
| Solubility | DMSO, Methanol, Pyridine |
| Pka | 15.09±0.20(Predicted) |
| Form | Oil |
| Color | Clear Colourless |
| Odor | at 100.00 %. sweet sandalwood woody waxy greasy creamy amyris |
| Odor Type | woody |
| LogP | 4.587 (est) |
| EPA Substance Registry System | 3-Cyclopentene-1-butanol, .alpha.,.beta.,2,2,3-pentamethyl- (65113-99-7) |
Sandalore is a premium synthetic sandalwood aroma raw material. It reproduces the elegant scent of natural sandalwood and is widely incorporated into perfumes, emollients and skin‑cleansing formulations. Beyond its outstanding fragrance performance, Sandalore features unique biological activity: it works as an agonist of skin olfactory receptor OR2AT4 to trigger calcium‑ion signaling in human keratinocytes. It facilitates keratinocyte proliferation and migration, effectively supporting epidermal regeneration and skin wound‑repair effects, which distinguishes it from natural sandalwood oil and other synthetic sandal‑note fragrances.
