Dihydromyricetin (DHM, also called Ampelopsin) is a natural flavonoid enriched in multiple Asian plants. Hovenia dulcis, in particular, has long been applied in traditional Chinese medicine to tackle alcohol poisoning and hangover discomfort (Liang et al. 2014). As a popular supplement raw material, DHM is primarily promoted for hangover relief, thanks to its function of reducing blood alcohol levels and its proven liver-protecting potential.
DHM delivers multiple health benefits, including antibacterial, anti-inflammatory, antioxidative and anti-cancer activities. It participates in balancing lipid and glucose metabolism and regulates programmed cell death, with negligible adverse influences on normal cells.
Notably, abundant studies confirm its remarkable hepatoprotective effects. Research focusing on acute liver failure demonstrates that DHM can ameliorate liver lesions caused by alcohol and other hazards (Liu et al. 2017). It effectively shields hepatic cells, relieves liver burden, and is widely adopted in functional food, health supplement and cosmetic industries.
| Dihydromyricetin Chemical Properties |
| storage temp. | -20°C |
| solubility | DMSO: ≥5mg/mL (warmed) |
| Melting point | 239-241 °C |
| pKa | 7.38±0.60(Predicted) |
| Boiling point | 780.7±60.0 °C(Predicted) |
| density | 1.808±0.06 g/cm3(Predicted) |
| form | powder |
| color | white to beige |
| Stability: | Hygroscopic |
| Cosmetics Ingredients Functions | SKIN CONDITIONING |
| InChI | InChI=1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1 |
| InChIKey | KJXSIXMJHKAJOD-LSDHHAIUSA-N |
| SMILES | [C@H]1(C2=CC(O)=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2C(=O)[C@@H]1O |
| LogP | 1.230 (est) |
| CAS DataBase Reference | 27200-12-0 |
| Safety Information |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29329990 |
| Storage Class | 11 - Combustible Solids |
Dihydromyricetin is processed under standardized extraction and purification procedures to guarantee stable purity and low impurity levels. Our products undergo rigorous laboratory testing before delivery, with full documentation including COA and MSDS available to support global export, formulation development and product registration. Supported by a stable supply chain, we are capable of fulfilling large-scale continuous orders to meet the raw material demands of health supplement, functional food and cosmetic manufacturers worldwide.
