Products Description of Acetylacetone CAS#123-54-6
Acetylacetone appears as a colorless to faint yellow transparent liquid with a characteristic odor. Its key physical constants include melting point -23℃, boiling point 140.4℃, refractive index (n²⁰D) of 1.4520 and relative density of 0.975.
It features excellent miscibility with ethanol, ether, chloroform, acetone, glacial acetic acid and other organic solvents, while also being soluble in water. Please note that the material is flammable and corrosive, and proper protective measures should be adopted during operation.
Acetylacetone Chemical Properties
| Melting point | -23 °C (lit.) |
| Boiling point | 140.4 °C (lit.) |
| density | 0.975 g/mL at 25 °C (lit.) |
| vapor density | 3.5 (vs air) |
| vapor pressure | 6 mm Hg ( 20 °C) |
| refractive index | n20/D 1.452(lit.) |
| Fp | 66 °F |
| storage temp. | Store below +30°C. |
| solubility | H2O: soluble1 in 8 parts |
| pka | 8.9(at 25℃) |
| form | Liquid |
| color | very deep green-yellow |
| Relative polarity | 0.571 |
| PH | 6 (200g/l, H2O, 20℃) |
| Odor | pleasant odor |
| explosive limit | 2.4-11.4%(V) |
| Water Solubility | 16 g/100 mL (20 ºC) |
| Merck | 14,81 |
| BRN | 741937 |
| Exposure limits | No exposure limit has been set. |
| Dielectric constant | 23.1（20℃） |
| InChIKey | YRKCREAYFQTBPV-UHFFFAOYSA-N |
| LogP | 0.68 at 20℃ |
| CAS DataBase Reference | 123-54-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Acetylacetone(123-54-6) |
| EPA Substance Registry System | Acetylacetone (123-54-6) |
| Hazard Codes | Xn,Xi |
| Risk Statements | 11-36/37/38-22-10-R22-R10-20/21/22-2017/10/22 |
| Safety Statements | 21-23-24/25-36-26-S24/25-S23-S21 |
| RIDADR | UN 2310 3/PG 3 |
| WGK Germany | 1 |
| RTECS | SA1925000 |
| F | 46288 |
| Autoignition Temperature | 662 °F |
| TSCA | Yes |
| HS Code | 2914 19 90 |
| HazardClass | 3 |
| PackingGroup | III |
| Hazardous Substances Data | 123-54-6(Hazardous Substances Data) |
| Toxicity | LC50 (4 hrs) in rats: 1000 ppm (Carpenter) |
Product Application of Acetylacetone CAS#123-54-6
As a vital intermediate for organic synthesis, acetylacetone reacts with guanidine to synthesize 2-amino-4,6-dimethylpyrimidine, acting as an essential raw material for pharmaceutical manufacturing.
It can be adopted as a solvent for cellulose acetate, functional additive for gasoline and lubricants, and drier for coatings and varnishes. Besides, it is applicable in fungicides and insecticides. Moreover, acetylacetone works as a catalyst and oxidation accelerator in petroleum cracking, hydrogenation and carbonylation reactions.
It is also utilized to eliminate metal oxides from porous solids and process polypropylenecatalysts. In European and American markets, more than 50% of acetylacetone demand is consumed in antidiarrheal pharmaceuticals and livestock feed additives.
