Triclosan Physicochemical Properties
Appearance:White crystalline powder with a subtle floral and phenolic aroma.
Solubility: Slightly soluble in water, moderately soluble in dilute alkalis, and freely soluble in organic solvents such as ethanol and acetone. It can dissolve in surfactants to form clear concentrated solutions.
Stability: Delivers excellent storage stability. No rapid decomposition occurs below 280–290°C. Only 2% of the active ingredient degrades after 14 hours of heating at 200°C. It suffers negligible degradation under prolonged UV irradiation, and its solutions maintain stability in both acidic and alkaline environments.
Volatility: Extremely low volatility accompanied by a light floral odor.
Parameters
| Melting point | 56-60 °C(lit.) |
| Boiling point | 290°C(lit.) |
| density | 1.4214 (rough estimate) |
| vapor pressure | 0.001Pa at 25℃ |
| refractive index | 1.4521 (estimate) |
| storage temp | 2-8°C |
| solubility | H2O: soluble12g/L at 20°C |
| form | Solid |
| pka | 7.9(at 25℃) |
| color | colorless or white |
| biological source | synthetic |
| Water Solubility | Soluble in ethanol, methanol, diethyl ether and sodium hydroxide solution (1M). Slightly soluble in water. |
| Merck | 14,9657 |
| BRN | 2057142 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | XEFQLINVKFYRCS-UHFFFAOYSA-N |
| LogP | 4.9 at 20℃ |
| CAS DataBase Reference | 3380-34-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Triclosan(3380-34-5) |
| EPA Substance Registry System | Triclosan (3380-34-5) |
Safety Information
| Hazard Codes | Xi,N |
| Risk Statements | 36/38-50/53-36/37/38 |
| Safety Statements | 26-39-46-60-61-24/25-22-36 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 2 |
| RTECS | KO1100000 |
| TSCA | Yes |
| HazardClass | 9 |
| PackingGroup | III |
| HS Code | 29095000 |
| Hazardous Substances Data | 3380-34-5(Hazardous Substances Data) |
| Toxicity | LD50 orl-rat: 3700 mg/kg 26UZAB 6,245,68/70 |
Triclosan (CAS#3380-34-5) is a high-efficiency broad-spectrum antibacterial raw material. It appears as white crystalline powder with a mild floral phenolic odor. Featuring ultra-low volatility and outstanding thermal and acid-alkali stability, it maintains stable antibacterial activity under various processing conditions. It is slightly soluble in water and soluble in ethanol, acetone, dilute alkalis and surfactant systems, facilitating flexible formulation development. Widely adopted to inhibit bacteria, fungi and other microorganisms, it is an ideal functional additive for personal care products, daily chemicals and industrial antibacterial supplies.
