Disodium edetate dihydrate CAS#6381-92-6
Products Description of Disodium Edetate Dihydrate (CAS No. 6381-92-6)Disodium ethylenediaminetetraacetate, also known as EDTA disodium, is a powerful chelating agent. Thanks to its high stability constant and broad coordination properties, it can form stable, water-soluble complexes with most metal ions, including iron, copper, calcium, magnesium and other polyvalent ions, thereby eliminating harmful reactions caused by these metal ions or their effects.

Parameters
Melting point | 250 °C (dec.)(lit.) |
Boiling point | >100 °C |
density | 1.01 g/mL at 25 °C |
bulk density | 700kg/m3 |
FEMA | 4520 | ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT |
refractive index | n |
Fp | >100℃ |
storage temp. | room temp |
solubility | 3 M NaOH: 100 mg/mL |
form | crystalline |
pka | pK1:1.99;pK2:2.67;pK3:6.16;pK4:10.26 (25°C) |
color | ≤5 (0.5 M)(APHA) |
PH | 4.0-5.5 (25℃, 0.1M in H2O) |
Odor | Odorless |
PH Range | 4 - 5 at 10 g/l at 23 °C |
biological source | synthetic (organic) |
Water Solubility | soluble |
λmax | λ: 260 nm Amax: 0.145 |
BRN | 3900609 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
InChIKey | QCDUWWPHAVXXQS-UHFFFAOYSA-L |
CAS DataBase Reference | 6381-92-6(CAS DataBase Reference) |
EPA Substance Registry System | Ethylenediaminetetraacetic acid disodium salt dihydrate (6381-92-6) |
Safety Information
Hazard Codes | Xi,Xn |
Risk Statements | 36-52/53-36/38-36/37/38-22 |
Safety Statements | 26-61-37/39-36/37/39-36 |
WGK Germany | 2 |
RTECS | AH4025000 |
F | 3 |
TSCA | Yes |
HS Code | 29224995 |
Toxicity | LD50 orally in Rabbit: > 2000 mg/kg |
Product Application of Disodium Edetate Dihydrate (CAS No. 6381-92-6)
1. Application Categories
Disodium edetate dihydrate belongs to a wide range of chemical and pharmaceutical categories, including organic chemicals, chelating agents, food additives, stabilizers and coagulants, nitrogen compounds, analytical standards, pharmaceutical intermediates, biochemical reagents, microorganisms, inorganic compounds and salts, solvents, professional reagents, titration solutions for volumetric analysis, chemical processing additives, acids, biochemistry, proteomics, standards and reference materials, chemical reagents, EDTA salts, pharmaceutical excipients, inorganic salts, raw drug intermediates, additives and preservatives.
2. Application Scenarios
Chelation & metal control: As a powerful chelating agent, it forms stable water-soluble complexes with most metal ions (iron, copper, calcium, magnesium, etc.), which is widely applied to remove or control trace metals in solutions.
Analytical & laboratory: Used as an analytical standard, professional reagent and titration solution for volumetric (complexometric) analysis, e.g. in EDTA titration for determining water hardness and metal ion content.
Pharmaceutical: Employed as a pharmaceutical excipient and raw drug intermediate, e.g. as a metal-sequestering agent in formulations and in detoxification therapy for heavy-metal poisoning.
Food industry: Applied as a food additive and preservative to prevent oxidation and discoloration caused by trace metal ions.
Industrial processing: Used as a stabilizer, coagulant and chemical processing additive in various manufacturing processes.
Biochemical research: Used in biochemistry and proteomics applications as a buffer component and reagent.
3. Technical Conditions & Standards
Implemented in accordance with applicable national standards: appearance of white powder, with purity and impurity limits (such as assay, heavy metals, chloride, iron and water content) subject to the corresponding grade and COA. Specific specifications should be confirmed against the batch Certificate of Analysis.
4. Production & Quality Control
Factory and Equipment Show — our disodium edetate dihydrate is produced in our own facility; please refer to the factory and equipment photos on this page. Every batch is tracked from raw material to release, with full documentation (COA, MSDS/SDS, packing list and invoice) provided with each shipment, following a quality control flow of incoming inspection, in-process monitoring, finished-batch analysis, release check and retained sample.
5. Packaging & Shipping
We offer export-grade packaging (type and net weight per package to be confirmed) and a minimum order quantity of 1 FCL (Full Container Load). Accepted Incoterms include FOB, CIF, EXW and CFR per order. Each shipment is accompanied by Commercial Invoice, Packing List, COA, MSDS and Bill of Lading, with the port of loading to be confirmed. Safe and professional loading ensures product quality is protected during transit.
6. After-Sales Service
We provide full technical documentation (COA, MSDS and TDS) with each order, real-time logistics tracking until delivery, sample service upon request (policy to be confirmed), and a dedicated contact who responds promptly to any quality or delivery concern.
7. Why Choose Us
We offer reliable quality with strict batch inspection and full traceability, competitive factory-direct pricing with transparent terms, fast quotation and order confirmation, and professional export experience in documentation and logistics.
8. Customer Cases
The following are placeholders to be replaced with your real cases. One example is an analytical reagent distributor sourcing EDTA disodium for volumetric titration end-users over a period of cooperation. Another is a pharmaceutical excipient buyer applying our product in chelating-agent applications for drug formulations.
9. FAQ
Common questions include the MOQ (1 FCL), whether samples are available (samples provided upon request), the documents provided (Commercial Invoice, Packing List, COA, MSDS and Bill of Lading as applicable), the applicable grade and purity standard (confirmed against the COA), and the accepted Incoterms (FOB, CIF, EXW, CFR per order).
10. Contact Us
For inquiries, please contact Mingxin Company (Shandong, China); company full name, contact person, email and telephone to be confirmed. We welcome your inquiry and look forward to a reliable and lasting cooperation.









