Ethylenediaminetetraacetic acid disodium salt, CAS#139-33-3
Ethylenediaminetetraacetic acid (commonly shortened to EDTA) features a strong affinity for binding with most metal cations, making it widely applicable across many industrial sectors. EDTA is available in various salt forms, including ethylenediaminetetraacetic acid disodium salt (EDTAS).
EDTA and its salts function as chelating agents in cosmetic products. EDTAS acts as a preservative, sequestrant and stabilizer in food applications. It is added to soft drinks formulated with ascorbic acid and disodium benzoate to reduce benzene formation. EDTA and its salts are also incorporated into paper and paperboard intended for food contact.
EDTAS is approved for use in animal feed, drinking water, and for the treatment of food-producing animals. In the textile industry, EDTA and its salts avoid color shifts of dyed goods caused by impurity metal ions. For pulp and paper manufacturing, they suppress metal ions from catalyzing the disproportionation of hydrogen peroxide, a common bleaching agent.
EDTAS finds usage in synthetic rubber production and serves as a corrosion inhibitor for carbon steel in industrial systems. Besides, EDTAS and EDTA tripotassium salt are the most widely used anticoagulants.
Ethylenediaminetetraacetic acid disodium salt Chemical Properties |
Melting point | 248 °C (dec.)(lit.) |
Boiling point | >100 °C |
density | 1.01 g/mL at 25 °C |
vapor pressure | 0Pa at 25℃ |
refractive index | n20/D 1.363 |
storage temp. | 2-8°C |
solubility | H2O: clear, colorless |
form | solution |
color | ≤5 (0.5 M)(APHA) |
Odor | at 100.00?%. odorless |
PH | 8.0±0.2 |
Water Solubility | Miscible with water. |
BRN | 3822669 |
Stability: | Hygroscopic |
Cosmetics Ingredients Functions | CHELATING |
LogP | -4.3 at 25℃ |
CAS DataBase Reference | 139-33-3(CAS DataBase Reference) |
EPA Substance Registry System | Ethylenediaminetetraacetic acid disodium salt (139-33-3) |
Absorption | cut-off at 268nm |
Safety Information |
Hazard Codes | Xn,C |
Risk Statements | 36/38-36/37/38-22-34-21/22 |
Safety Statements | 26-36-37/39-45-36/37/39-36/37 |
WGK Germany | 2 |
RTECS | AH4410000 |
TSCA | Yes |
HS Code | 29224999 |
Hazardous Substances Data | 139-33-3(Hazardous Substances Data) |
Toxicity | mouse,LD50,intraperitoneal,260mg/kg (260mg/kg),Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 52, Pg. 126S, 1956. |
Ethylenediaminetetraacetic acid disodium salt (CAS#139-33-3)
Product Application
Ethylenediaminetetraacetic acid (EDTA) belongs to aminopolycarboxylic acids and acts as a hexadentate ligand. It can chelate metal ions, particularly metal cations, to form stable octahedral coordination complexes.
Ethylenediaminetetraacetic acid disodium salt (Disodium EDTA) is widely known as a blood anticoagulant and is associated with pseudothrombocytopenia. It binds to calcium ions in blood to block coagulation reactions, so it is a standard additive for routine hematological examinations. It can also boost the antibacterial performance of lysozyme.
In chelation therapy, EDTA binds calcium ions to help dilate arteries and dissolve atheromatous plaques for atherosclerotic vascular conditions. Additionally, EDTA chelation may reduce oxidative injury, restraining blood lipid peroxidation linked to liver fibrosis.
Beyond medical and laboratory uses, Disodium EDTA serves as an efficient chelating agent across industries:
Food & Beverage: Works as sequestrant, stabilizer and preservative to control trace metal ions, prevent discoloration and slow deterioration; reduces benzene generation in drinks containing ascorbic acid and sodium benzoate.
Cosmetics & Personal Care: Stabilizes formulations, shields active ingredients from metal-induced degradation.
Textile & Dyeing: Eliminates interference from metal impurities to maintain consistent dye color.
Pulp & Paper: Suppresses metal ions from decomposing hydrogen peroxide bleaching agent.
Synthetic Rubber & Industrial Circulation: Applied in rubber synthesis and acts as a carbon steel corrosion inhibitor.
Animal Nutrition: Approved for addition into animal feed and drinking water for food-producing animals.
Product Specifications
CAS No.: 139-33-3
Molecular Formula: C₁₀H₁₄N₂Na₂O₈
Synonyms: Ceftriaxone Impurity 21, WANKLYN'S EDTA, Disodium EDTA
Appearance: White powder
MOQ: 1 FCL
Packaging & Transportation
We adopt standard industrial packaging for Disodium EDTA, normally packed in 25kg kraft paper bags or plastic woven bags with inner PE liner. Custom packing specifications (label design, marking, palletization) are available upon customer request.
The product is non-dangerous goods under regular transport rules. It should be kept away from strong acids, strong oxidants and direct sunlight during transit. Storage warehouse requires dry, cool and well-ventilated conditions to avoid moisture absorption and caking. We can arrange FCL, LCL and consolidated shipment according to your logistics plan, and provide full set of shipping documents including packing list, commercial invoice, COA, MSDS.
Factory & Equipment Show
Our production base is equipped with mature synthesis, crystallization, drying and automatic packaging lines. Strict closed production workflow effectively controls product purity and particle uniformity.
Independent QC laboratory is equipped with precision testing instruments to monitor raw material input, intermediate parameters and finished product indexes. Every batch will go through full inspection before release to guarantee stable quality consistent with COA.
Lead Time & Stock Arrangement
In-stock goods: Ready for shipment within 2–3 working days after receiving payment
New production order: Production cycle 7–10 working days subject to order quantity
We maintain regular safety stock for steady demand, and arrange priority schedule for urgent orders after communication.
After-sales Service & Quality Commitment
Batch quality traceability: Each lot corresponds to independent COA and test record. If any quality discrepancy confirmed on arrival, we will negotiate reasonable solutions such as replenishment or compensation.
Technical support: Our technical team offers guidance on product storage, dosing method and application problems for your production.
Document support: We can supply MSDS, TDS, SGS test report and other certification files required for customs clearance or registration.
Communication guarantee: We keep timely follow-up on shipment status, update logistics information and respond to your inquiries promptly.
