Piroctone olamine CAS#68890-66-4
Piroctone olamine (INN, also referred to as piroctone ethanolamine, brand name Octopirox) is a chemical compound widely used for fungal infection treatment. It is the ethanolamine salt of piroctone, a hydroxamic acid derivative.
Piroctone olamine Chemical Properties |
Melting point | 134.0 to 138.0 °C |
Boiling point | 135-235℃[at 101 325 Pa] |
density | 1.1[at 20℃] |
vapor pressure | 0-0Pa at 20-25℃ |
storage temp. | Inert atmosphere,2-8°C |
solubility | Chloroform (Slightly, Sonicated), Methanol (Slightly) |
pka | 5.9-7.4[at 20 ℃] |
form | Solid |
color | White to Off-White |
Water Solubility | 400-50000mg/L at 20-25℃ |
Merck | 14,7502 |
Major Application | agriculture |
Cosmetics Ingredients Functions | PRESERVATIVE |
InChI | InChI=1S/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7- 11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2 |
InChIKey | BTSZTGGZJQFALU-UHFFFAOYSA-N |
SMILES | C(N)CO.C(C1=CC(C)=CC(=O)N1O)C(C)CC(C)(C)C |
LogP | 1.05-3.86 at 20-25℃ |
CAS DataBase Reference | 68890-66-4(CAS DataBase Reference) |
Safety Information |
WGK Germany | 2 |
RTECS | UU7786150 |
HS Code | 2933399090 |
Storage Class | 11 - Combustible Solids |
Hazard Classifications | Aquatic Chronic 3 |
Piroctone olamine CAS#68890‑66‑4
H2: Product Application
Piroctone olamine is commonly compounded with other functional ingredients in shampoo formulations. It can effectively reduce dandruff formation while bringing hair‑conditioning benefits. Relevant research indicates that piroctone olamine can induce cell apoptosis and shows notable in‑vivo efficacy against myeloma.
H3: Hair‑care Cosmetic Field
As a high‑efficiency anti‑dandruff active raw material, it is widely incorporated into anti‑dandruff shampoo, scalp toners, hair conditioners and rinse‑off hair care products. It suppresses scalp‑related microorganism reproduction, relieves scalp itching, and delivers gentle conditioning effect to hair fibers. It features good compatibility with most surfactants and cosmetic auxiliary materials for stable cosmetic formula preparation.
H3: Personal‑care & Skin‑care Formulation
Beyond hair‑care products, it can be applied in deodorants, body wash and mild anti‑acne preparations. Thanks to its broad‑spectrum antimicrobial property, it can also play an auxiliary preservative role in cosmetic systems within the recommended dosage range.
H3: Pharmaceutical & Biochemical Research
Except cosmetic usages, piroctone olamine is adopted for biochemical study and pharmaceutical‑related research. Scientific findings reveal its apoptosis‑inducing property and promising in‑vivo activity for myeloma‑related research projects.
H2: Core Product Advantages
H3: Excellent Formula Compatibility
This white‑powder raw material can be well blended with most cosmetic raw materials. It adapts to a relatively wide pH range and helps produce clear and stable finished cosmetic products without complex pre‑treatment.
H3: Dual‑function Performance
It combines anti‑dandruff scalp‑care effect with auxiliary bacteriostatic and preservative functions, simplifying formula design for cosmetic manufacturers.
H3: Strict Batch‑wise Quality Assurance
Each production batch will go through lab inspection on purity, appearance and impurity indicators before delivery to satisfy cosmetic‑grade raw‑material requirements.
H2: Packaging, Storage & Transportation
H3: Standard Packaging Specification
Standard bulk packing: 25 kg fibre drum with inner food‑grade PE bag. Smaller‑size packing such as 1 kg /5 kg aluminum foil bags are available for lab‑scale and pilot‑test orders. Custom‑made packaging solutions are negotiable for long‑term large‑volume customers.
H3: Storage Recommendations
Store in cool, dry and well‑ventilated warehouse. Keep containers tightly sealed. Avoid direct sunlight, high‑temperature environment and moisture. Keep separate from strong oxidizing substances. Under proper storage conditions, the shelf‑life reaches 24 months.
H3: Transport Notes
Ship as general fine‑chemical goods. Prevent package breakage, dampness and heavy squeezing during transit. Please refer to MSDS for complete handling and transportation guidance.
H2: Delivery Schedule
H3: In‑stock Goods
Shipment within 2‑3 working days upon payment confirmation.
H3: New‑production Orders
Production lead‑time: 7‑10 working days for newly‑manufactured batches.
Remark: The above lead‑time does not include international ocean transit time. Minor schedule adjustment may happen in peak production or logistics seasons, we will send real‑time order updates.
H2: Export Supporting Documents
We can provide complete export documents for overseas customs clearance and incoming‑goods inspection:
‑ Batch‑specific COA (Certificate of Analysis)
‑ MSDS (Material Safety Data Sheet)
‑ Commercial invoice, packing list and other customs‑required export papers
H2: Target End‑Users
‑ Cosmetic manufacturers for anti‑dandruff shampoo and personal‑care products
‑ Fine‑chemical raw‑material compounding factories
‑ Biochemical laboratories and pharmaceutical research institutions
‑ Global cosmetic‑ingredient trading companies and bulk‑material distributors
H2: Factory & Production Capacity
Our workshop implements standardized production workflow for piroctone olamine. Independent QC laboratory carries out sampling testing for every batch before shipment. Factory‑and‑equipment introduction documents can be provided for customer audit upon request. Both spot bulk supply and long‑term framework supply contracts are supported for stable large‑volume buyers.
H2: After‑sales & Technical Support
H3: Pre‑sales Technical Consulting
Our technical team can provide reference dosage suggestions and formula‑compatibility tips for cosmetic‑grade formulation according to customer’s product development needs.
H3: After‑sales Response
We offer working‑day feedback within 24 hours for quality‑related enquiries. If delivered goods fail to meet contracted specifications, we will coordinate feasible resolution plans. Technical guidance for product application is available; losses caused by improper customer‑side formulation or storage will not be covered for quality compensation.
H2: FAQ
H3: What is your MOQ for piroctone olamine?
Our bulk‑order MOQ is 1 FCL (Full Container Load). Small‑quantity trial lots for laboratory R&D can be discussed separately.
H3: Can I get testing samples for formula development?
Samples are available upon request; sample freight will be quoted separately.
H3: What is the recommended adding dosage in shampoo formulation?
Typical usage dosage in anti‑dandruff shampoo ranges from 0.05%‑0.1%. Excessive addition should be avoided; please refer to regional cosmetic regulatory requirements before mass‑productionClariant.
H3: Is long‑term supply contract acceptable for cosmetic factories?
Long‑term supply framework agreements can be negotiated for large‑volume stable purchasers to stabilize raw‑material cost and delivery cycles.
H3: What international trade terms can you support?
We support EXW, FOB, CIF and other mainstream trade terms. We cooperate with experienced freight forwarders to arrange port‑to‑port shipment.
