Ketone Musk (Musk Ketone) Related Information
Pleasant and Classic Musk Aroma
Ketone musk boasts a sweet, animal-like musk scent that enhances the depth and richness of fragrance formulations, bringing a classic and pleasant aroma to the end products.
Long-Lasting Scent Performance
Its aroma is soft yet enduring, delivering excellent longevity that makes it highly suitable for perfumes and various fragrance products requiring a long-lasting scent.
Stable Physical and Chemical Properties
Ketone musk features a relatively high melting point and boiling point, demonstrating remarkable thermal stability and chemical stability in different application scenarios.
Good Compatibility with Fragrance Materials
It is soluble in benzyl benzoate, animal oils, and essential oils, enabling easy blending with a wide range of fragrance ingredients and enhancing its applicability in fragrance formulation.
Product Details
Musk Ketone (CAS No.: 81-14-1)
Musk Ketone is a crucial synthetic fragrance compound with a molecular formula of C₁₄H₁₈N₂O₅ and a molecular weight of 294.303. It presents as pale yellow crystals, usually in powder or flake form, and is distinguished by a sweet, animal-like musk aroma that is soft and long-lasting.
Musk Ketone is insoluble in water and ethanol but dissolves easily in benzyl benzoate, animal oils, and essential oils. It has a melting point ranging from 135–139 °C, a density of approximately 1.2 ± 0.1 g/cm³, a boiling point of 369.0 ± 42.0 °C at 760 mmHg, and a flash point of 153.2 ± 20.7 °C.
Product Usage
Musk Ketone is widely utilized as an important synthetic fragrance and scent fixative. In the flavor and fragrance industry, it is commonly employed in formulating various fragrance blends, endowing products with a unique and long-lasting musky aroma—especially suitable for sweet, oriental, and heavy fragrance types.
In the cosmetics industry, it is often added to perfumes, powders, creams, and similar products. It not only enriches the overall fragrance profile but also extends the scent’s staying power on the skin.
Additionally, while its application in the pharmaceutical field is limited due to potential toxicity and environmental concerns, pharmacological research shows that it can stimulate the central nervous system, respiratory center, and heart. It may also promote glandular secretion, dilate coronary arteries to increase coronary blood flow, and assist in improving blood circulation, reducing swelling, and relieving pain.
Parameter
| Product Name: | Musk ketone |
| Synonyms: | 2-Acetyl-5-tert-butyl-4,6-dinitro-1,3-dimethylbenzene;3',5'-Dinitro-4'-tert-butyl-2',6'-dimethylacetophenone;3, 5-Dinitro-4-t-butyl-2, 6-dimethylacetophenone;Ketone Moschus,4-tert-Butyl-2,6-dimethyl-3,5-dinitroacetophenone, Musk ketone;Musk ketone,4-tert-Butyl-2,6-dimethyl-3,5-dinitroacetophenone, Ketone Moschus;Musk ketone 0;Ketone Moschus >=97.0% (N);1-(4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl)-ethanon |
| CAS: | 81-14-1 |
| MF: | C14H18N2O5 |
| MW: | 294.3 |
| EINECS: | 201-328-9 |
| Product Categories: | PP;KetonesAlphabetic;Analytical Standards;AromaticsAnalytical Standards;Chemical Class;Life Sciences Standards;Aromatic Acetophenones & Derivatives (substituted);M;METI - MZChromatography;Natural Compounds;Natural CompoundsAnalytical Standards;Nitro CompoundsChemical Class;OtherMore...Close...;Cosmetics;Food & Feed ADDITIVES;Organics |
| Mol File: | 81-14-1.mol |
Musk ketone Chemical Properties
| Melting point | 134-137 °C |
| Boiling point | 436.08°C (rough estimate) |
| Density | 1.2051 (rough estimate) |
| Vapor pressure | 0.001Pa at 25℃ |
| Refractive index | 1.5110 (estimate) |
| Fp | 2 °C |
| Storage temp | 2-8°C |
| Solubility | DMSO : 250 mg/mL (849.47 mM; Need ultrasonic) |
| Form | Solid |
| Color | White to off-white |
| Odor | at 10.00 % in benzyl benzoate. fatty musk soapy dry floral powdery |
| Odor Type | musk |
| Biological source | synthetic |
| Water Solubility | Insoluble (<0.1 g/100 mL at 20 ºC) |
| BRN | 2062638 |
| Stability | Stable. Incompatible with strong oxidizing agents, strong acids, strong bases. |
| InChIKey | WXCMHFPAUCOJIG-UHFFFAOYSA-N |
| LogP | 4.24 at 25℃ |
| CAS DataBase Reference | 81-14-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 2,6-Dimethyl-3,5-dinitro-4-t-butylacetophenone(81-14-1) |
| EPA Substance Registry System | Musk ketone (81-14-1) |
