Tetrasodium pyrophosphate CAS#7722-88-5
Commonly abbreviated as TSPP, tetrasodium pyrophosphate is a versatile inorganic phosphate compound widely adopted across laboratory, industrial and food sectors. In laboratory work, it functions effectively as a buffering substance. A typical application is preparing EDTA‑tetrasodium pyrophosphate extraction buffer, which supports the detection and analysis of microcystin contained within soil samples.
This chemical exists as an odourless white powder or granular solid. It carries multiple functional properties and can serve as a water softener, thickener and dispersant in different formulations. It works as a wool degreasing agent, metal surface cleaner, as well as a builder for soap and synthetic detergent systems. It also acts as a sequestering reagent for metal electrodeposition processes.
In oral care products, it helps inhibit tartar formation and is incorporated into toothpaste and dental floss formulations. Researchers also apply it as a chelating agent in antimicrobial related experiments. Besides these uses, it is approved as a food additive, frequently added to processed foods including chicken nuggets, crab meat and canned tuna for quality preservation and texture adjustment.

| Tetrasodium pyrophosphate Chemical Properties |
| Melting point | 80 °C |
| Boiling point | 93.8 °C |
| density | 2.53 g/mL at 25 °C(lit.) |
| vapor pressure | 0Pa at 20℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | H2O: 0.1 M at 20 °C, clear, colorless |
| form | Granular |
| color | White |
| Specific Gravity | 2.534 |
| Odor | Odorless |
| PH Range | 10.3 |
| Water Solubility | Soluble in water. Insoluble in ethyl alcohol. |
| Sensitive | Hygroscopic |
| Merck | 14,9240 |
| Exposure limits | NIOSH: TWA 5 mg/m3 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| Cosmetics Ingredients Functions | BUFFERING CHELATING ANTICAKING ORAL CARE |
| InChI | 1S/4Na.H4O7P2/c;;;;1-8(2,3)7-9(4,5)6/h;;;;(H2,1,2,3)(H2,4,5,6)/q4*+1;/p-4 |
| InChIKey | FQENQNTWSFEDLI-UHFFFAOYSA-J |
| SMILES | [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O |
| LogP | -3.42 |
| CAS DataBase Reference | 7722-88-5(CAS DataBase Reference) |
| EPA Substance Registry System | Tetrasodium pyrophosphate (7722-88-5) |
| Safety Information |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-41-22 |
| Safety Statements | 26-36-39 |
| OEB | B |
| OEL | TWA: 5 mg/m3 |
| WGK Germany | 3 |
| RTECS | UX7350000 |
| TSCA | TSCA listed |
| HS Code | 28353990 |
| Storage Class | 13 - Non Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 |
| Hazardous Substances Data | 7722-88-5(Hazardous Substances Data) |
Product Application Of Tetrasodium pyrophosphate CAS#7722-88-5
1. Application Scenarios
1.1 Food Formulation & Food Additive
Tetrasodium pyrophosphate (TSPP) is a mildly alkaline food additive with a pH value around 10 and moderate water solubility (0.8 g/100 ml at 25°C). It acts as a coagulant, emulsifier and sequestrant in food systems.
For instant non-cooked pudding: It serves as a coagulant to deliver expected thickening effects without heating.
For cheese products: It helps control melting performance and restrains fat separation during processing and storage.
For powdered beverage products: It works as an excellent dispersant for malted milk and chocolate drink powder, avoiding particle agglomeration and improving rehydration effect when mixed with water.
For canned tuna: It suppresses undesirable crystal precipitation, maintaining a good appearance and texture of canned fish meat.
1.2 Industrial & Laboratory Uses
Beyond food-grade application, TSPP is widely used in many industrial fields. It can act as a water softener, metal ion sequestering agent and dispersing agent in detergent, cleaning and electroplating formulas. In labs, it is frequently prepared into buffer solutions for extraction and testing such as microcystin analysis. It also finds application in oral care products to control tartar buildup.
2. Packaging Specification
Standard package: 25kg woven bag with PE inner liner, moisture-proof design for powder products.
Bulk packing: 1000kg jumbo bag is available for large FCL orders.
Label information: Each package marks product name, CAS number, net weight, batch number, production date and shelf life, complying with international import documentation requirements. Custom label service is supported upon request.
3. Transportation & Storage Guidance
3.1 Transportation Notes
This product belongs to general inorganic chemicals, non-dangerous goods. Keep the packages intact during transit, avoid heavy rain and moisture invasion. Prevent sharp objects from puncturing the bags. Mix shipment with strong acid is not recommended.
3.2 Storage Requirements
Store in a dry, cool and ventilated warehouse. The inner bag must remain tightly sealed to prevent moisture absorption and caking. Keep away from acidic materials. Proper storage can maintain its flowability and stable functional performance.
4. Delivery Schedule
Fast delivery time
In-stock goods: Shipment can be arranged within 2–3 working days after payment confirmation.
New production order: 7–10 working days for production, inspection and loading, subject to the factory production schedule.
We can provide packing photos before shipment for your confirmation.
5. After-sales Service
Document supply: We can provide COA, TDS, MSDS and other supporting certificates. Food-grade batch certificates are available for food application clients.
Logistics follow-up: We share the tracking number once the cargo departs, and update shipping status actively.
Technical consultation: Our team can offer guidance on dosage, dissolution method and formula matching.
Quality solution: If quality inconsistency is verified after receiving goods, we will communicate promptly to reach a reasonable settlement plan.
6. Customer Cases
We supply food-grade tetrasodium pyrophosphate to food processing factories, canned food manufacturers, beverage powder enterprises and detergent production plants. Our clients mainly apply it in canned seafood, dairy and cheese processing, instant dessert mixes and industrial cleaning formulations. We support stable long-term FCL bulk supply.
7. FAQ
Q1: Is TSPP the same as sodium pyrophosphate?
A1: Yes. Tetrasodium pyrophosphate is also known as sodium pyrophosphate, tetrasodium diphosphate, abbreviated as TSPP. They refer to the same substance.
Q2: Is this product food grade?
A2: Our supply covers food grade and industrial grade. Please confirm the grade you need before ordering, as their impurity indicators and applicable scenarios differ greatly.
Q3: Will it cake easily?
A3: TSPP is easy to absorb moisture. As long as you keep the package sealed and store it under dry conditions, caking can be effectively avoided.
Q4: Can I get samples to test the performance first?
A4: Yes, sample service is available for laboratory and formulation testing. You may place bulk FCL orders after testing and quality confirmation.






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