Imidazolidinyl Urea (CAS 39236-46-9) is a high-efficiency, non-aromatic, polar and hydrophilic antimicrobial preservative widely formulated in personal care, cosmetic and topical pharmaceutical products. Featuring excellent water solubility and stable chemical properties, this synthetic urea-based compound can be easily incorporated into aqueous formulations without affecting the color, odor, viscosity and texture of finished products, making it one of the most versatile and cost-effective preservatives in the cosmetic industry.
As a broad-spectrum antimicrobial agent, Imidazolidinyl Urea delivers strong inhibitory effects against a wide range of harmful microorganisms, including gram-positive bacteria, gram-negative bacteria, fungi and yeast. It effectively suppresses microbial reproduction and growth during product storage and usage, preventing product deterioration, spoilage, odor generation and contamination. With stable bacteriostatic performance under conventional pH and temperature ranges of cosmetic production, it provides long-term and reliable protection for water-based daily chemical formulations.
This preservative is extensively applied in diverse end products. Its typical application scenarios include cosmetics, facial cleansers, shampoos, conditioners, body washes, deodorants, hand lotions, body creams, moisturizing emulsions and various skin care aqueous products. In addition to daily personal care formulations, it is also commonly used in therapeutic topical ointments, external skin creams and other dermatological preparations to ensure the microbial safety of topical medicinal products and extend shelf life.
Imidazolidinyl Urea features outstanding formulation compatibility, showing good stability with most common cosmetic raw materials, surfactants and emulsifiers. It has no irritating odor, low skin irritation risk and will not damage the mild formula properties of daily care products. Suitable for daily and sensitive skin care formulations, it meets the mainstream safety standards for cosmetic preservatives and is widely recognized and adopted by global daily chemical manufacturers.
In summary, Imidazolidinyl Urea (CAS 39236-46-9) serves as an ideal preservative solution for daily chemicals and topical pharmaceutical products, combining broad-spectrum antibacterial activity, excellent water solubility, high stability and good compatibility, effectively guaranteeing product safety, stability and service life.
| Imidazolidinyl urea Chemical Properties |
| Melting point | 141-143℃ |
| Boiling point | 514.04°C (rough estimate) |
| density | 1.4245 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.6910 (estimate) |
| storage temp. | 2-8°C |
| solubility | Soluble in water and in glycerol, but insoluble in almost all organic solvents. |
| pka | 7.41±0.10(Predicted) |
| form | Liquid |
| color | Clear |
| Water Solubility | soluble |
| Merck | 14,4916 |
| Stability: | Stable. |
| Major Application | pharmaceutical (small molecule) |
| Cosmetics Ingredients Functions | PRESERVATIVE |
| Cosmetic Ingredient Review (CIR) | Imidazolidinyl urea (39236-46-9) |
| InChI | 1S/C11H16N8O8/c20-2-18-4(6(22)16-10(18)26)14-8(24)12-1-13-9(25)15-5-7(23)17-11(27)19(5)3-21/h4-5,20-21H,1-3H2,(H2,12,14,24)(H2,13,15,25)(H,16,22,26)(H,17,23,27) |
| InChIKey | ZCTXEAQXZGPWFG-UHFFFAOYSA-N |
| SMILES | OCN1C(NC(=O)NCNC(=O)NC2N(CO)C(=O)NC2=O)C(=O)NC1=O |
| LogP | 0.9 at 20℃ |
| CAS DataBase Reference | 39236-46-9(CAS DataBase Reference) |
| EPA Substance Registry System | Imidurea (39236-46-9) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36 |
| Safety Statements | 26-36 |
| WGK Germany | 2 |
| RTECS | YT7365000 |
| TSCA | TSCA listed |
| HS Code | 29332990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Skin Sens. 1B |
