LDAO CAS#1643-20-5

Lauryl Dimethyl Amine Oxide (LDAO)

CAS No.: 1643-20-5

Molecular Formula: C₁₄H₃₁NO

Standard Aliases & Trade Names

Oxydededimethyllaurylamine, Refan, Cocoamine oxide derivative, Lauramine Oxide, DDAO

Premium Physical Property Advantages

This product is provided in high-purity white solid form with uniform crystal particle size, free from lumps and foreign impurities. It boasts stable physical properties during long-term storage and cross-ocean transportation, with no deliquescence or discoloration under normal sealed preservation. The solid state features high active content without redundant water solvent, greatly reducing transportation cost per effective component. It can be rapidly dissolved in water and various polar organic solvents at moderate temperature, bringing flexible dosing and compounding operation for different production formulas.

Core Functional & Performance Advantages

  1. Unique pH-responsive amphoteric surfactant structure

    As a classic amine oxide amphoteric surfactant, it presents cationic performance under acidic conditions and nonionic features in neutral and alkaline environments. It achieves excellent compatibility with anionic, cationic, nonionic and other amphoteric surfactants, and generates remarkable synergistic effects when compounded with AES, sodium sulfate and betaine surfactants to upgrade overall formula performance.

  2. Powerful foaming stabilization and self-thickening capacity

    It acts as an efficient foam booster and stabilizer, generating delicate, dense and long-lasting foam that remains stable even in hard water with high mineral content. It possesses natural thickening effects without extra thickening additives, simplifying formulation design for transparent cleansing products.

  3. Mild, skin-friendly and irritation-mitigating characteristic

    It can significantly lower the irritation of anionic surfactants to human skin and mucous membranes. With low irritancy, it is the ideal functional additive for sensitive skin care products, infant cleansing supplies and mild facial detergents, and also carries mild broad-spectrum bacteriostatic properties against common bacteria.

  4. Eco-friendly and multi-functional auxiliary agent

    The product is readily biodegradable and conforms to global environmental protection standards for cosmetics and detergents. It integrates multiple functions including detergency, emulsification, antistatic property, softening and calcium soap dispersion. It tolerates high electrolyte concentration without precipitation, perfectly suitable for concentrated cleaning formulas and industrial heavy oil degreasers.

  5. Wide-range industrial application scenarios

  • Personal care & cosmetic raw materials: shampoo, body wash, facial cleanser, hand sanitizer and shaving foam

  • Household & industrial cleaning products: dishwashing liquid, multi-purpose surface cleaner, liquid laundry detergent

  • Textile chemical auxiliaries: fiber antistatic agent and fabric softener

  • Biochemistry research reagent: non-denaturing detergent for membrane protein extraction and purification

LDAO CAS#1643-20-5

DDAO is a far-red fluorogenic substrate for esterase and lipase.

LDAO Chemical Properties

Melting point 132-133 °C(lit.)
Boiling point 371.32°C (rough estimate)
density 0.996 g/mL at 20 °C
vapor pressure 0Pa at 25℃
refractive index n20/D 1.378
Fp 113°C (closed cup)(235
storage temp. -20°C
solubility Ethanol:15.0(Max Conc. mg/mL);65.38(Max Conc. mM)
DMF:3.0(Max Conc. mg/mL);1.31(Max Conc. mM)
DMSO:0.1(Max Conc. mg/mL);0.44(Max Conc. mM)
PBS (pH 7.2):0.1(Max Conc. mg/mL);0.44(Max Conc. mM)
pka4.79±0.40(Predicted)
form A crystalline solid
color White to off-white
Specific Gravity0.97
PH7.0-9.0 (25°C, 0.1M in H2O)
Water Solubility Insoluble in water.
Sensitive Hygroscopic
BRN 1769927
Stability:Stable. Incompatible with strong oxidizing agents. Combustible.
Cosmetics Ingredients FunctionsCLEANSING
SURFACTANT - CLEANSING
PERFUMING
HAIR CONDITIONING
ANTISTATIC
SURFACTANT - FOAM BOOSTING
SURFACTANT - HYDROTROPE
VISCOSITY CONTROLLING
Cosmetic Ingredient Review (CIR)LDAO (1643-20-5)
InChI1S/C14H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-15(2,3)16/h4-14H2,1-3H3
InChIKeySYELZBGXAIXKHU-UHFFFAOYSA-N
SMILESCCCCCCCCCCCC[N+](C)([O-])C
LogP1.85 at 20℃
EPA Substance Registry SystemLauryldimethylamine oxide (1643-20-5)

Safety Information

Hazard Codes C
Risk Statements 34-52/53
Safety Statements 26-36/37/39-45-27
RIDADR UN 3259 8/PG 2
WGK Germany 2
RTECS JR6650000
3-10
TSCA TSCA listed
HazardClass 8
PackingGroup III
HS Code 29299090
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 2
Eye Dam. 1
Skin Irrit. 2
Hazardous Substances Data1643-20-5(Hazardous Substances Data)
Toxicitymouse,LD50,intraperitoneal,375mg/kg (375mg/kg),French Medicament Patent Document. Vol. #4264M,

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