4-Amino-N-methylbenzamide CAS#6274-22-2

Name: 4-Amino-N-methylbenzamide CAS#6274-22-2 - Tianjin Mingxin New Materials Group Co., Ltd.
Brand: Tianjin Mingxin New Materials Group Co., Ltd.
Availability: InStock

Superior Thermal Stability for High-Temperature Processing

Boasting a melting point of 181 °C and boiling point over 360 °C, the compound maintains outstanding thermal stability, well suited for high-temperature synthesis and industrial manufacturing processes.

Low Volatility for Safer Operation

It features an ultra-low vapor pressure of 1.72 × 10⁻⁵ mmHg @ 25 °C, which minimizes vaporization and the risk of inhalation exposure, enabling secure storage and routine handling.

Favorable Solubility in Organic Media

Good solubility in methanol supports straightforward dissolution and formulation, ideal for use as a chemical intermediate in organic synthesis and pharmaceutical manufacturing.

Consistent & Predictable Physicochemical Characteristics

Well-defined molecular properties including density, refractive index and polarizability, paired with a stable crystalline structure, guarantee uniform quality and dependable performance for R&D and industrial-scale production.

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4-Amino-N-methylbenzamide (CAS: 6274-22-2) is a high-value specialty fine chemical. It carries the molecular formula C₈H₁₀N₂O with a molecular weight of 150.18.

Key physicochemical properties: density 1.137 g/cm³, melting point 181 °C, boiling point 364.1±25.0 °C (760 mmHg), flash point 174.0±23.2 °C, and vapor pressure 1.72E-05 mmHg @25 °C.

The product presents as white crystals and is soluble in methanol. For preservation, sealed storage at ambient temperature is required.

Its well-characterized structural constants include molar refractive index 44.11, molar volume 132.0 cm³/mol, and polarizability 17.48 × 10⁻²⁴ cm³, supporting stable and repeatable performance for synthesis and R&D.

4-Amino-N-methylbenzamide Chemical Properties

Melting point	181 °C
Boiling point	364.1±25.0 °C(Predicted)
Density	1.137
Storage temp	Keep in dark place,Inert atmosphere,Room temperature
Solubility	soluble in Methanol
Form	powder to crystal
Pka	15.84±0.46(Predicted)
Color	White to Light yellow to Light orange
CAS DataBase Reference	6274-22-2(CAS DataBase Reference)
Hazard Codes	Xi
HazardClass	IRRITANT
HS Code	29242990

4-Amino-N-methylbenzamide (CAS 6274-22-2) is a high-purity specialty fine chemical widely adopted in organic synthesis and pharmaceutical intermediate research. It appears as white crystals, soluble in methanol, with well-defined and stable physicochemical constants: molecular formula C₈H₁₀N₂O, molecular weight 150.18, melting point 181 °C, boiling point 364.1±25.0 °C (760 mmHg) and ultra-low vapor pressure at ambient temperature. Characterized by high thermal stability and predictable molecular structural parameters, this product delivers consistent batch-to-batch performance. Please store it tightly sealed at room temperature for best preservation.

Applications

Pharmaceutical Intermediate

It acts as a key intermediate for active pharmaceutical ingredient (API) synthesis, supporting the development of kinase inhibitor-related compounds such as Defactinib.

Organic Synthesis

Functions as a versatile molecular building block for constructing sophisticated nitrogen-bearing organic compounds.