METRAFENONE | CAS#220899-03-6
Metrafenone is an active ingredient belonging to the benzophenone chemical class. Structurally built upon a benzophenone skeleton, the compound contains two substituted phenyl rings. One phenyl ring is substituted with methoxy groups at the 2-, 3-, and 4-positions and a methyl group at the 6-position. The second phenyl ring bears methyl, bromine and methoxy substituents at the 2-, 3-, and 6-positions correspondingly.
Functioning as a dual-action fungicide with outstanding protectant and curative properties, metrafenone is extensively applied to suppress powdery mildew diseases on cereal crops and grapevines. It features a unique mode of action categorized as FRAC Group 50, which interferes with the actin cytoskeleton formation of fungal pathogens. Unlike many conventional fungicides, it generates no cross-resistance with triazoles, strobilurins and other common fungicide varieties, making it a vital component in anti-resistance integrated disease management programmes.
The active substance inhibits the whole life cycle of powdery mildew fungi, restraining spore germination, mycelial growth and pathogen sporulation. Benefiting from translaminar activity and slight vapor-phase mobility, it achieves uniform protection across leaf surfaces and newly emerging plant tissues, delivering stable and long-lasting control efficacy under diverse field conditions.
METRAFENONE Chemical Properties |
Boiling point | 534.4±50.0 °C(Predicted) |
density | 1.310±0.06 g/cm3(Predicted) |
Henry's Law Constant | 7.6×100 mol/(m3Pa) at 25℃, Maniere et al. (2011) |
Major Application | agriculture |
InChI | 1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3 |
InChIKey | AMSPWOYQQAWRRM-UHFFFAOYSA-N |
SMILES | COc1ccc(Br)c(C)c1C(=O)c2c(C)cc(OC)c(OC)c2OC |
LogP | 5.190 (est) |
EPA Substance Registry System | Methanone, (3-bromo-6-methoxy-2-methylphenyl)(2,3,4-trimethoxy-6-methylphenyl)- (220899-03-6) |
Safety Information |
Hazard Codes | N |
Risk Statements | 50/53 |
Safety Statements | 60-61 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | 3 |
Storage Class | 11 - Combustible Solids |
Hazard Classifications | Aquatic Acute 1 |
Metrafenone is a high-performance fungicidal active ingredient widely incorporated into pesticide formulations. It delivers reliable protection for various vegetation and commercial agricultural crops against destructive fungal diseases.
Production & Delivery Lead Time
In-stock inventory: Goods can be arranged for shipment within 2–3 working days upon receipt of formal order.
New production arrangement: Custom manufacturing requires a lead time of 7–10 working days.
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