This multi-compendial grade propylene glycol is a transparent hygroscopic liquid solvent and moisturizer with minimum purity reaching 99.5%, fully conforming to USP, EP and FCC international standards.
For pharmaceutical manufacturing, it acts as a premium parenteral excipient with strictly controlled endotoxin level ≤0.5 EU/mL, perfectly qualified as a solvent for injectable formulations.
In cosmetic & personal care production, it functions as a mild moisturizer validated by OECD 439 skin irritation test, guaranteeing gentle and safe application in all topical skincare formulas.
Food-grade FCC specification complies with US FDA regulation 21 CFR 184.1666, widely adopted as anti-freeze carrier in food processing systems.
Featuring low toxicity and outstanding freeze resistance (freezing point -59°C per ASTM D1384 standard), this glycol performs reliably as solvent and anti-freeze medium across various industrial scenarios.
Complete technical files including COA, test reports and compliance certificates are available upon request.
Propylene glycol Chemical Properties
| Melting point | -60 °C (lit.) |
| Boiling point | 187 °C (lit.) |
| Density | 1.036 g/mL at 25 °C (lit.) |
| Vapor density | 2.62 (vs air) |
| Vapor pressure | 0.08 mm Hg ( 20 °C) |
| Refractive index | n20/D 1.432(lit.) |
| FEMA | 2940 | PROPYLENE GLYCOL |
| Fp | 225 °F |
| Storage temp. | Store at +5°C to +30°C. |
| Solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| Pka | 14.49±0.20(Predicted) |
| Form | Viscous Liquid |
| Color | APHA: ≤10 |
| Specific Gravity | 1.038 (20/20℃)1.036～1.040 |
| PH | 6-8 (100g/l, H2O, 20℃) |
| Odor | at 100.00 %. odorless very slight alcoholic |
| Odor Type | odorless |
| Optical Rotation | -0.11° (C=1.00g/100ml, CHCL3) |
| Biological source | synthetic |
| Explosive limit | 2.4-17.4%(V) |
| Water Solubility | miscible |
| Sensitive | Hygroscopic |
| Merck | 14,7855 |
| JECFA Number | 925 |
| BRN | 1340498 |
| Dielectric constant | 32.0 |
| InChIKey | DNIAPMSPPWPWGF-UHFFFAOYSA-N |
| LogP | -0.92 |
| Surface tension | 35.44mN/m at 298.15K |
| CAS DataBase Reference | 57-55-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Propylene glycol(57-55-6) |
| EPA Substance Registry System | Propylene glycol (57-55-6) |
Safety Information
| Safety Statements | 24/25 |
| WGK Germany | 1 |
| RTECS | TY2000000 |
| Autoignition Temperature | 779 °F |
| TSCA | Yes |
| HS Code | 29053200 |
| Hazardous Substances Data | 57-55-6(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: 19400 - 36000 mg/kg LD50 dermal Rabbit 20800 mg/kg |
Propylene Glycol, CAS No. 57-55-6, is a versatile multi-purpose raw material favored by manufacturers worldwide, thanks to outstanding solvency and low toxic profile.
Complying with USP standards, this product features ultra-low endotoxin (≤0.5 EU/mL), making it a reliable solvent for oral medicines and transdermal pharmaceutical preparations.
For cosmetic manufacturing, it acts as a gentle hydrating agent validated by OECD 439 irritation testing, effectively boosting moisture retention in toners, body lotions and essence serums.
Our FCC-grade propylene glycol complies with FDA regulation 21 CFR 184.1666 and works as a secure anti-freeze medium in food production workflows.
Bearing a freezing point of -59°C in accordance with ASTM D1384 testing standards, its superior anti-freeze performance also makes it an essential solvent and anti-freeze carrier for all types of industrial scenarios.
We can supply complete technical papers, certificates and test reports to meet the compliance requirements of different sectors.
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