Rhodamine B, CAS# 81‑88‑9
Also known as C.I. Food Red 15, this substance presents as green crystalline particles or reddish‑violet fine powdered solid. It features a molecular weight of 479.1 g/mol. According to the NFPA‑704 M hazard rating system, its hazard classification is rated as Health 1, Flammability 1 and Reactivity 0, indicating low‑to‑moderate health risk, low flammability and stable chemical properties without obvious reactive hazards under regular handling conditions. The product possesses excellent water‑soluble performance and can dissolve readily in aqueous solution. Chemically, it is classified as an organic chloride salt, with N‑[9‑(2‑carboxyphenyl)‑6‑(diethylamino)‑3H‑xanthen‑3‑ylidene]‑N‑ethylethanaminium serving as its characteristic counterion. As a typical amphoteric dyestuff, it delivers outstanding fluorescent properties, and is widely adopted as a high‑performance fluorochrome for multiple industrial and laboratory research scenarios.
Rhodamine B Chemical Properties |
Melting point | 210-211 (dec.)(lit.) |
bulk density | 250kg/m3 |
density | 0.79 g/mL at 20 °C |
refractive index | 1.6500 (estimate) |
Fp | 12 °C |
storage temp. | room temp |
solubility | H2O: soluble1mg/mL |
form | Solid |
Colour Index | 45170 |
color | Green |
PH | 3-4 (10g/l, H2O, 20℃) |
Water Solubility | SOLUBLE |
ε(extinction coefficient) | 104500-115800 at 542-554nm in methanol |
Merck | 14,8183 |
BRN | 4119648 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
Major Application | cleaning products |
Cosmetics Ingredients Functions | COLORANT |
InChI | 1S/C28H30N2O3.ClH/c1-5-29(6-2)19-13-15-23-25(17-19)33-26-18-20(30(7-3)8-4)14-16-24(26)27(23)21-11-9-10-12-22(21)28(31)32;/h9-18H,5-8H2,1-4H3;1H |
InChIKey | PYWVYCXTNDRMGF-UHFFFAOYSA-N |
SMILES | [Cl-].CCN(CC)c1ccc2c(OC3=CC(\C=CC3=C2c4ccccc4C(O)=O)=[N+](/CC)CC)c1 |
LogP | 1.9-2 |
CAS DataBase Reference | 81-88-9(CAS DataBase Reference) |
IARC | 3 (Vol. 16, Sup 7) 1987 |
NIST Chemistry Reference | Rhodamine b(81-88-9) |
EPA Substance Registry System | Rhodamine B (81-88-9) |
Safety Information |
Hazard Codes | Xn,Xi,F |
Risk Statements | 22-41-68-67-36-11-40-20/21/22-52/53 |
Safety Statements | 7-16-24/25-26-36/37/39-39-36-22 |
WGK Germany | 3 |
RTECS | BP3675000 |
TSCA | TSCA listed |
HS Code | 32041300 |
Storage Class | 11 - Combustible Solids |
Hazard Classifications | Acute Tox. 4 Oral |
Hazardous Substances Data | 81-88-9(Hazardous Substances Data) |
Toxicity | LD50 i.v. in rats: 89.5 mg/kg (Webb) |
Rhodamine B serves as a versatile functional dyestuff with broad‑ranging application scenarios. It is widely deployed as a coloring agent, most notably for paper dyeing industry. Besides dyeing purposes, it acts as a sensitive analytical reagent for qualitative and quantitative detection of multiple metal elements including antimony, bismuth, cobalt, niobium, gold, manganese, mercury, molybdenum, tantalum, thallium and tungsten. It is also well‑recognized as a classic biological stain for biological sample staining work. Meanwhile, it has obtained provisional listing for potential application in pharmaceutical formulations and cosmetic products.
In biological research fields, Rhodamine B is frequently adopted for investigative studies, such as anti‑reactive oxygen species and hepatic fibrosis‑targeted drug‑delivery systems constructed from salvianolic acid B‑loaded mesoporous silica nanoparticles. Furthermore, this product can be applied in environmental testing work for analyzing dyes and their corresponding metabolites in environmental samples.
Delivery Lead Time
Fast shipment is available for this item. For goods from existing stock, delivery can be arranged within 2‑3 working days. For newly manufactured bulk orders, the production cycle will take 7‑10 working days.
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